This is set by an individual user preference, but has a global default that can be set to disable caching. Setting the Jive system property jive.apps.cache-control.default = "false" should do the trick.
Note: This change will have a significant impact on overall system performance and should ONLY be used in dedicated app development environments.
I have updated Jive Apps Developer Community: Disabling App Caching During Development on our developer community. A new section at the bottom explains how to disable app caching by default.